) in the eotaxin-3 gene above normal frequency is an indicator of ee or a marker of disease risk, prognosis, and/or a response to therapy. Another embodiment of the invention is a method to mitigate ee by providing an inhibitor to eotaxin-3 and/or a receptor, such as ccr3, for binding eotaxin-3 in a cell, such as a mast cell or an eosinophil, under conditions sufficient to inhibit eotaxin-3 binding to the receptor. Another embodiment of the invention is a gene expression profile for ee comprising seq. reputable online generic viagra Id nos. 1-1620. Another embodiment of the invention is a method to evaluate ee by gene expression profiles, where evaluation encompasses assessment of disease propensity, of disease severity, of therapy efficacy, of therapy compliance, etc. buy cheap viagra In one embodiment, ee is evaluated by determining an expression profile of at least one gene in the esophagus of the patient, where the gene is selected from seq id nos. viagra canada online 1-1620. In one embodiment, ee is evaluated by determining an expression profile of at least one gene in the patient, where the gene is selected from group consisting of seq id nos. buy viagra cheap 1-1620. The expression profile of the selected gene(s) is then compared to the expression profile of that same gene in an individual that does not have ee. viagra best price usa The patient's propensity for ee is evaluated by determining if the gene in the patient is either over-expressed ≧1. buy viagra online 5 times or is under-expressed ≧1. 5 times compared to the same gene in the expression profile in the individual without ee. This propensity is evaluated by determining the extent that over-expression or under-expression exceeds 1. buy generic viagra on line 5, the identify of the gene over-expressed or under-expressed, and/or the number of genes that are over-expressed or under-expressed. The patient's propensity for ee is higher based on at least one of the farther the over-expression or under-expression is from 1. 5, the gene is from seq id no. 1-42, and/or the greater the number of genes that are over-expressed or under-expressed. In one embodiment the gene is seq id no. 1. In one embodiment, the patient lacks at least one clinical and/or physical symptoms of ee. buy generic viagra online In one embodiment, the cell is an esophageal cell. Another embodiment of the invention is a method to evaluate a compound's contribution to the pathophysiology of ee. At least one cell, referred to as the test cell, is exposed to the compound, and an expression profile of at least one gene selected from the group consisting of seq id nos. 1-1620 in the cell(s) is compared to an expression profile of at least one gene selected from the group consisting of seq id nos. viagra best price usa 1-1620 in a cell of an individual without ee, referred to as the control cell. The contribution of the compound. does natural viagra work